This EJournal Club series will engage rheumatologists, and other interested clinicians in an examination, discussion, and assessment of the most recent peer-reviewed literature on rheumatic diseases. Dr. Leonard Calabrese will lead an interactive discussion with the lead author of a top evidence-based journal article. Sirukumab, a human anti-interleukin-6 monoclonal antibody webcast features Dr. Michael Weinblatt of Harvard University and Dr. Leonard Calabrese, Cleveland Clinic. The video was produced by the Cleveland Clinic Foundation Center for Continuing Education and the Cleveland Clinic RJ Fasenmyer Center for Clinical Immunology. Interested in related CME education? Visit http://www.ccfcme.org/ejournalvideos