Many growth factors, hormones, cytokines, and nutrients activate the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT) pathway. The PI3K-AKT signaling is involved in the control of numerous critical cellular processes such as apoptosis, cell proliferation, and the cell cycle. Dysregulated PI3K/AKT signaling is involved in the pathophysiology of a range of diseases including cancer, cardiovascular disease, type 2 diabetes, and others. Learn about the proteins involved in the pathway and how the mutation of AKT1 at E17K contributes to tumorigenesis. Bio-Rad offers a range of highly validated PrecisionAb Antibodies to study this signaling pathway successfully. You can also download a copy of a poster for this pathway and others such as EGF R, mTOR, NF-kB, and more. View additional details at https://www.bio-rad-antibodies.com/cancer-research-posters.html Subscribe to the Bio-Rad channel: https://www.youtube.com/user/BioRadLifeScience?sub_confirmation=1 We Are Bio-Rad. Our mission: To provide useful, high-quality products and services that advance scientific discovery and improve healthcare. At Bio-Rad, we are united behind this effort. These two objectives are the driving force behind every decision we make, from developing innovative ideas to building global solutions that help solve our customers' greatest challenges. #WesternBlotting #pi3K #CancerPathway Connect with Bio-Rad Online: Website: http://www.bio-rad.com/ LinkedIn: https://www.linkedin.com/company/1613226/ Facebook: https://www.facebook.com/biorad/ Twitter: https://twitter.com/BioRadLifeSci Instagram: @BioRadLabs Snapchat: @BioRadLabs ©2022 Bio-Rad is a trademark of Bio-Rad Laboratories, Inc. in certain jurisdictions. All trademarks used herein are the property of their respective owner. Music used by permission granted by royalty-free license from Pond5.com